Benjamin Tycko
Affiliations: | Columbia University College of Physicians and Surgeons, New York, NY, United States |
Website:
http://www.cumc.columbia.edu/dept/taub/faculty-tycko.htmlGoogle:
"Benjamin Tycko"
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Publications
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| Gonda TA, Fang J, Salas M, et al. (2020) A DNA hypomethylating drug alters the tumor microenvironment and improves the effectiveness of immune checkpoint inhibitors in a mouse model of pancreatic cancer. Cancer Research |
| Do C, Dumont ELP, Salas M, et al. (2020) Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs. Genome Biology. 21: 153 |
| Yu YE, Xing Z, Do C, et al. (2020) Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models. Progress in Brain Research. 251: 1-28 |
| Delahaye F, Do C, Kong Y, et al. (2018) Genetic variants influence on the placenta regulatory landscape. Plos Genetics. 14: e1007785 |
| Youn A, Kim KI, Rabadan R, et al. (2018) A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes. Bmc Medical Genomics. 11: 98 |
| Wu HC, Do C, Andrulis IL, et al. (2018) Breast Cancer Family History and Allele-Specific DNA Methylation in the Legacy Girls Study. Epigenetics. 1-23 |
| Safyan RA, Gonda T, Tycko B, et al. (2018) Phase II open-label, single-center study evaluating safety and efficacy of pembrolizumab following induction with the hypomethylating agent azacitidine in patients with advanced pancreatic cancer after failure of first-line therapy. Journal of Clinical Oncology. 36: TPS534-TPS534 |
| Jiang Y, Loh YE, Rajarajan P, et al. (2017) The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics |
| Do C, Shearer A, Suzuki M, et al. (2017) Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era. Genome Biology. 18: 120 |
| Lee JH, Lee AJ, Dang LH, et al. (2017) Candidate gene analysis for Alzheimer's disease in adults with Down syndrome. Neurobiology of Aging |