Dennis D. Cunningham

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Molecular Biology
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"Dennis Cunningham"
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Publications

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Pai KS, Cunningham DD. (2002) Geldanamycin specifically modulates thrombin-mediated morphological changes in mouse neuroblasts. Journal of Neurochemistry. 80: 715-8
Pai KS, Mahajan VB, Lau A, et al. (2001) Thrombin receptor signaling to cytoskeleton requires Hsp90. The Journal of Biological Chemistry. 276: 32642-7
Mahajan VB, Pai KS, Lau A, et al. (2000) Creatine kinase, an ATP-generating enzyme, is required for thrombin receptor signaling to the cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 97: 12062-7
Weinstein JR, Lau AL, Brass LF, et al. (1998) Injury-related factors and conditions down-regulate the thrombin receptor (PAR-1) in a human neuronal cell line. Journal of Neurochemistry. 71: 1034-50
Donovan FM, Cunningham DD. (1998) Signaling pathways involved in thrombin-induced cell protection. The Journal of Biological Chemistry. 273: 12746-52
Guttridge DC, Lau A, Tran L, et al. (1997) Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1. The Journal of Biological Chemistry. 272: 24117-20
Donovan FM, Pike CJ, Cotman CW, et al. (1997) Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5316-26
Guttridge DC, Cunningham DD. (1996) Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain. Journal of Neurochemistry. 67: 498-507
Pike CJ, Vaughan PJ, Cunningham DD, et al. (1996) Thrombin attenuates neuronal cell death and modulates astrocyte reactivity induced by beta-amyloid in vitro. Journal of Neurochemistry. 66: 1374-82
Grabham P, Cunningham DD. (1995) Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. Journal of Neurochemistry. 64: 583-91
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