Leonard Freedman

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Cell Biology
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"Leonard Freedman"
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Shen Q, Bai Y, Chang KC, et al. (2011) Liver X receptor-retinoid X receptor (LXR-RXR) heterodimer cistrome reveals coordination of LXR and AP1 signaling in keratinocytes. The Journal of Biological Chemistry. 286: 14554-63
Schmidt A, Kimmel DB, Bai C, et al. (2010) Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology. The Journal of Biological Chemistry. 285: 17054-64
Greger JG, Fursov N, Cooch N, et al. (2010) Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase (Molecular and Cellular Biology (2007) 27, 5, (1904-1913)) Molecular and Cellular Biology. 30: 1568
Chang KC, Wang Y, Oh IG, et al. (2010) Estrogen receptor beta is a novel therapeutic target for photoaging. Molecular Pharmacology. 77: 744-50
Chang KC, Shen Q, Oh IG, et al. (2008) Liver X receptor is a therapeutic target for photoaging and chronological skin aging. Molecular Endocrinology (Baltimore, Md.). 22: 2407-19
Cheskis BJ, Greger J, Cooch N, et al. (2008) MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways. Steroids. 73: 901-5
Krum SA, Miranda-Carboni GA, Hauschka PV, et al. (2008) Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. The Embo Journal. 27: 535-45
Cheskis BJ, Greger JG, Nagpal S, et al. (2007) Signaling by estrogens. Journal of Cellular Physiology. 213: 610-7
Greger JG, Fursov N, Cooch N, et al. (2007) Phosphorylation of MNAR promotes estrogen activation of phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 27: 1904-13
Lipfert L, Fisher JE, Wei N, et al. (2006) Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation. Molecular Endocrinology (Baltimore, Md.). 20: 516-33
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