Patrick L. Iversen

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Pharmacology, Molecular Biology, Cell Biology
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"Patrick Iversen"
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Publications

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Annalora AJ, Jozic M, Marcus CB, et al. (2018) Alternative splicing of the vitamin D receptor modulates target gene expression and promotes ligand-independent functions. Toxicology and Applied Pharmacology
Annalora AJ, O'Neil S, Bushman JD, et al. (2018) A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors. Oncotarget. 9: 30568-30586
Annalora AJ, Marcus CB, Iversen PL. (2017) Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Warren TK, Whitehouse CA, Wells J, et al. (2015) A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection. Mbio. 6
Heald AE, Iversen PL, Saoud JB, et al. (2014) Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies. Antimicrobial Agents and Chemotherapy. 58: 6639-47
Geller BL, Marshall-Batty K, Schnell FJ, et al. (2013) Gene-silencing antisense oligomers inhibit acinetobacter growth in vitro and in vivo. The Journal of Infectious Diseases. 208: 1553-60
Schnell FJ, Crumley SL, Mourich DV, et al. (2013) Development of novel bioanalytical methods to determine the effective concentrations of phosphorodiamidate morpholino oligomers in tissues and cells. Bioresearch Open Access. 2: 61-6
Iversen PL, Warren TK, Wells JB, et al. (2012) Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections. Viruses. 4: 2806-30
Panchal RG, Geller BL, Mellbye B, et al. (2012) Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis. Nucleic Acid Therapeutics. 22: 316-22
Ma W, Lin Y, Xuan W, et al. (2012) Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs. Oncogene. 31: 1024-33
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