Ruth Sonntag Nussenzweig, M. D., Ph.D.

Affiliations: 
1965-1980 Department of Preventive Medicine New York University, New York, NY, United States 
 1980-2018 Department of Molecular Parasitology New York University, New York, NY, United States 
Area:
Molecular Biology, Genetics, Cell Biology
Website:
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000300405
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"Ruth Sonntag Nussenzweig"
Bio:

Sonntag Nussenzweig was born Ruth Sonntag in Vienna, Austria, to a secular Jewish family in which both her parents were physicians. In 1939, after the Anschluss, the Sonntags fled to São Paulo, Brazil. While attending the University of São Paulo School of Medicine, she became involved in leftist politics and met Victor Nussenzweig, her future husband and lifelong research partner. After receiving her M.D., Nussenzweig moved to Paris for a research fellowship. In 1963, she did further graduate work at the NYU laboratory of immunologist Zoltán Óváry.

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Parents

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Zoltán Óváry post-doc NYU
Baruj Benacerraf post-doc 1963-1964 New York University (Neurotree)

Children

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Elaine Guadelupe Rodrigues grad student 1994-1995 New York University (Chemistry Tree)
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Publications

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de Camargo TM, de Freitas EO, Gimenez AM, et al. (2018) Prime-boost vaccination with recombinant protein and adenovirus-vector expressing Plasmodium vivax circumsporozoite protein (CSP) partially protects mice against Pb/Pv sporozoite challenge. Scientific Reports. 8: 1118
Gimenez AM, Lima LC, Françoso KS, et al. (2017) Vaccine Containing the Three Allelic Variants of the Plasmodium vivax Circumsporozoite Antigen Induces Protection in Mice after Challenge with a Transgenic Rodent Malaria Parasite. Frontiers in Immunology. 8: 1275
Li X, Huang J, Zhang M, et al. (2016) Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice. Vaccine
Huang J, Li X, Coelho-Dos-Reis JG, et al. (2015) Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria. Journal of Immunological Methods
Teixeira LH, Tararam CA, Lasaro MO, et al. (2014) Immunogenicity of a prime-boost vaccine containing the circumsporozoite proteins of Plasmodium vivax in rodents. Infection and Immunity. 82: 793-807
Nussenzweig RS, Krettli AU. (2014) Breakthroughs towards a malaria vaccine. Historia, Ciencias, Saude--Manguinhos. 18: 559-64
Mishra S, Nussenzweig RS, Nussenzweig V. (2012) Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal activity. Journal of Immunological Methods. 377: 47-52
Camacho AG, Teixeira LH, Bargieri DY, et al. (2011) TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium. MemóRias Do Instituto Oswaldo Cruz. 106: 167-71
Mishra S, Rai U, Shiratsuchi T, et al. (2011) Identification of non-CSP antigens bearing CD8 epitopes in mice immunized with irradiated sporozoites. Vaccine. 29: 7335-42
Zhang M, Fennell C, Ranford-Cartwright L, et al. (2010) The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands. The Journal of Experimental Medicine. 207: 1465-74
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