Jan Jongstra

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Immunology, Molecular Biology, Cell Biology
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"Jan Jongstra"
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Publications

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Siu A, Virtanen C, Jongstra J. (2011) PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells. Oncotarget. 2: 1134-44
Chang M, Kanwar N, Feng E, et al. (2010) PIM kinase inhibitors downregulate STAT3(Tyr705) phosphorylation. Molecular Cancer Therapeutics. 9: 2478-87
Smith AL, Ganesh L, Leung K, et al. (2007) Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. The Journal of Experimental Medicine. 204: 421-30
Liu L, Cara DC, Kaur J, et al. (2005) LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration. The Journal of Experimental Medicine. 201: 409-18
Harrison RE, Sikorski BA, Jongstra J. (2004) Leukocyte-specific protein 1 targets the ERK/MAP kinase scaffold protein KSR and MEK1 and ERK2 to the actin cytoskeleton. Journal of Cell Science. 117: 2151-7
Wong MJ, Malapitan IA, Sikorski BA, et al. (2003) A cell-free binding assay maps the LSP1 cytoskeletal binding site to the COOH-terminal 30 amino acids. Biochimica Et Biophysica Acta. 1642: 17-24
Wang C, Hayashi H, Harrison R, et al. (2002) Modulation of Mac-1 (CD11b/CD18)-mediated adhesion by the leukocyte-specific protein 1 is key to its role in neutrophil polarization and chemotaxis. Journal of Immunology (Baltimore, Md. : 1950). 169: 415-23
Cao MY, Shinjo F, Heinrichs S, et al. (2001) Inhibition of anti-IgM-induced translocation of protein kinase C beta I inhibits ERK2 activation and increases apoptosis. The Journal of Biological Chemistry. 276: 24506-10
Jongstra-Bilen J, Misener VL, Wang C, et al. (2000) LSP1 modulates leukocyte populations in resting and inflamed peritoneum. Blood. 96: 1827-35
Jongstra-Bilen J, Wielowieyski A, Misener V, et al. (1999) LSP1 regulates anti-IgM induced apoptosis in WEHI-231 cells and normal immature B-cells. Molecular Immunology. 36: 349-59
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