Francis M. Hughes
Affiliations: | University of North Carolina, Charlotte, Charlotte, NC, United States |
Area:
Cell BiologyGoogle:
"Francis Hughes"
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| Dunton CL, Purves JT, Hughes FM, et al. (2018) Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X in rat urothelial cells. International Urology and Nephrology |
| Inouye BM, Hughes FM, Sexton SJ, et al. (2018) The Emerging Role of Inflammasomes as Central Mediators in Inflammatory Bladder Pathology. Current Urology. 11: 57-72 |
| Hughes F, Sexton S, Leidig P, et al. (2018) Mp09-16 Pharmacological Inhibition Of The Nlrp3 Inflammasome Prevents Bladder Decompensation In A Rat Model Of Chronic Bladder Outlet Obstruction The Journal of Urology. 199 |
| Lütolf R, Hughes FM, Inouye BM, et al. (2017) NLRP3/IL-1β mediates denervation during bladder outlet obstruction in rats. Neurourology and Urodynamics |
| Hughes FM, Sexton SJ, Jin H, et al. (2017) Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β. American Journal of Physiology. Renal Physiology. ajprenal.00128.2017 |
| Hughes FM, Kennis JG, Youssef MN, et al. (2016) The NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome Mediates Inflammation and Voiding Dysfunction in a Lipopolysaccharide-Induced Rat Model of Cystitis. Journal of Clinical & Cellular Immunology. 7 |
| Hughes FM, Hill HM, Wood CM, et al. (2015) The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction. The Journal of Urology |
| Hughes FM, Turner DP, Todd Purves J. (2015) The potential repertoire of the innate immune system in the bladder: expression of pattern recognition receptors in the rat bladder and a rat urothelial cell line (MYP3 cells). International Urology and Nephrology |
| Hughes FM, Vivar NP, Kennis JG, et al. (2014) Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation American Journal of Physiology - Renal Physiology. 306: F299-F308 |
| Hughes FM, Corn AG, Nimmich AR, et al. (2013) Cyclophosphamide Induces an Early Wave of Acrolein-Independent Apoptosis in the Urothelium. Advances in Bioscience and Biotechnology (Print). 4 |