Swati P. Deb

Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Molecular Biology, Oncology
"Swati Deb"
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Vaughan CA, Pearsall I, Singh S, et al. (2016) Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter. Oncotarget
Deb SP, Singh S, Deb S. (2014) MDM2 overexpression, activation of signaling networks, and cell proliferation. Sub-Cellular Biochemistry. 85: 215-34
Vaughan CA, Deb SP, Deb S, et al. (2014) Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites. Oncotarget. 5: 417-27
Frum RA, Singh S, Vaughan C, et al. (2014) The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing. Nucleic Acids Research. 42: 926-40
Singh S, Ramamoorthy M, Vaughan C, et al. (2013) Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells. Cell Death and Differentiation. 20: 558-66
Vaughan C, Deb SP, Deb S. (2013) Generation of p53 knock-down cell lines. Methods in Molecular Biology (Clifton, N.J.). 962: 193-9
Vaughan CA, Singh S, Windle B, et al. (2012) Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl. Genes & Cancer. 3: 491-502
Vaughan CA, Frum R, Pearsall I, et al. (2012) Allele specific gain-of-function activity of p53 mutants in lung cancer cells. Biochemical and Biophysical Research Communications. 428: 6-10
Vaughan CA, Singh S, Windle B, et al. (2012) p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity. Archives of Biochemistry and Biophysics. 518: 79-88
Yeudall WA, Vaughan CA, Miyazaki H, et al. (2012) Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration. Carcinogenesis. 33: 442-51
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