Irving Goldschneider

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Immunology, Molecular Biology
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"Irving Goldschneider"
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Lai L, Zhang M, Goldschneider I. (2012) Recombinant IL-7/HGFβ efficiently induces transplantable murine hematopoietic stem cells. The Journal of Clinical Investigation. 122: 3552-62
Lai L, Jin J, Hodio J, et al. (2011) A human recombinant IL-7/HGFα hybrid cytokine enhances T-cell reconstitution in mice after syngeneic bone marrow transplantation. Transplantation. 92: 516-22
Jin J, Goldschneider I, Lai L. (2011) In vivo administration of the recombinant IL-7/hepatocyte growth factor β hybrid cytokine efficiently restores thymopoiesis and naive T cell generation in lethally irradiated mice after syngeneic bone marrow transplantation. Journal of Immunology (Baltimore, Md. : 1950). 186: 1915-22
Lai L, Jin J, Goldschneider I. (2011) In vivo antitumor activity of a recombinant IL-7/HGFbeta hybrid cytokine in mice. Cancer Research. 71: 61-7
Staron M, Yang Y, Liu B, et al. (2010) gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis. Blood. 115: 2380-90
Lai L, Zeff RA, Goldschneider I. (2006) A recombinant single-chain IL-7/HGFbeta hybrid cytokine induces juxtacrine interactions of the IL-7 and HGF (c-Met) receptors and stimulates the proliferation of CFU-S12, CLPs, and pre-pro-B cells. Blood. 107: 1776-84
Wei C, Lai L, Goldschneider I. (2002) Pre-pro-B cell growth-stimulating factor (PPBSF) upregulates IL-7Ralpha chain expression and enables pro-B cells to respond to monomeric IL-7. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 823-32
Lai L, Goldschneider I. (2001) Cutting edge: Identification of a hybrid cytokine consisting of IL-7 and the beta-chain of the hepatocyte growth factor/scatter factor. Journal of Immunology (Baltimore, Md. : 1950). 167: 3550-4
Wei C, Zeff R, Goldschneider I. (2000) Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7R alpha, terminal deoxynucleotidyltransferase, and c mu expression. Journal of Immunology (Baltimore, Md. : 1950). 164: 1961-70
McKenna SD, Goldschneider I. (1994) A selective culture system for generating terminal deoxynucleotidyl transferase-positive lymphoid cells in vitro. V. Detection of stage-specific pro-B-cell stimulating activity in medium conditioned by mouse bone marrow stromal cells. Developmental Immunology. 3: 181-95
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