Karen M. Spach, Ph.D.

2005 University of Wisconsin, Madison, Madison, WI 
Nutrition, Immunology
"Karen Spach"


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Colleen E. Hayes grad student 2005 UW Madison
 (The vitamin D endocrine system in the control of experimental autoimmune encephalomyelitis.)
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Diehl SA, McElvany B, Noubade R, et al. (2014) G proteins gαi1/3 are critical targets for bordetella pertussis toxin-induced vasoactive amine sensitization Infection and Immunity. 82: 773-782
Lu C, Diehl SA, Noubade R, et al. (2010) Endothelial histamine H1 receptor signaling reduces blood-brain barrier permeability and susceptibility to autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 107: 18967-72
Spach KM, Case LK, Noubade R, et al. (2010) Multiple linked quantitative trait loci within the Tmevd2/Eae3 interval control the severity of experimental allergic encephalomyelitis in DBA/2J mice. Genes and Immunity. 11: 649-59
Nashold FE, Spach KM, Spanier JA, et al. (2009) Estrogen controls vitamin D3-mediated resistance to experimental autoimmune encephalomyelitis by controlling vitamin D3 metabolism and receptor expression Journal of Immunology. 183: 3672-3681
Spach KM, Noubade R, McElvany B, et al. (2009) A single nucleotide polymorphism in Tyk2 controls susceptibility to experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 182: 7776-83
Spach KM, Blake M, Bunn JY, et al. (2009) Cutting edge: the Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice. Journal of Immunology (Baltimore, Md. : 1950). 182: 1789-93
Lu C, Pelech S, Zhang H, et al. (2008) Pertussis toxin induces angiogenesis in brain microvascular endothelial cells. Journal of Neuroscience Research. 86: 2624-40
Noubade R, Saligrama N, Spach K, et al. (2008) Autoimmune disease-associated histamine receptor H 1 alleles exhibit differential protein trafficking and cell surface expression Journal of Immunology. 180: 7471-7479
Pedersen LB, Nashold FE, Spach KM, et al. (2007) 1,25-dihydroxyvitamin D3 reverses experimental autoimmune encephalomyelitis by inhibiting chemokine synthesis and monocyte trafficking. Journal of Neuroscience Research. 85: 2480-90
Spach KM, Nashold FE, Dittel BN, et al. (2006) IL-10 signaling is essential for 1,25-dihydroxyvitamin D3-mediated inhibition of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 177: 6030-7
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