Kyle N. Cowan, Ph.D.
Affiliations: | 2000 | University of Toronto, Toronto, ON, Canada |
Area:
Pathology, Cell BiologyGoogle:
"Kyle Cowan"Parents
Sign in to add mentor| Marlene Rabihovitch | grad student | 2000 | University of Toronto | |
| (Coordinated induction of apoptosis and extracellular matrix resorption reverses severe pulmonary vascular disease.) | ||||
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Publications
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| Almasi S, Crawford Parks TE, Ravel-Chapuis A, et al. (2021) Differential regulation of autophagy by STAU1 in alveolar rhabdomyosarcoma and non-transformed skeletal muscle cells. Cellular Oncology (Dordrecht) |
| Crawford Parks TE, Marcellus KA, Langill J, et al. (2017) Novel Roles for Staufen1 in Embryonal and Alveolar Rhabdomyosarcoma via c-myc-dependent and -independent events. Scientific Reports. 7: 42342 |
| Wild B, St-Pierre ME, Langlois S, et al. (2017) Elastase and matrix metalloproteinase activities are associated with pulmonary vascular disease in the nitrofen rat model of congenital diaphragmatic hernia. Journal of Pediatric Surgery |
| Faye MD, Beug ST, Graber TE, et al. (2015) IGF2BP1 controls cell death and drug resistance in rhabdomyosarcomas by regulating translation of cIAP1. Oncogene. 34: 1532-41 |
| Faye MD, Graber TE, Beug S, et al. (2014) Abstract 4256: Characterization of the cellular inhibitor of apoptosis 1 (cIAP1) IRES trans-acting factors and their contribution to apoptotic resistance in rhabdomyosarcomas Cancer Research. 74: 4256-4256 |
| Cowan KN, Leung WC, Mar C, et al. (2005) Caspases from apoptotic myocytes degrade extracellular matrix: a novel remodeling paradigm. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1848-50 |
| Cowan KN, Heilbut A, Humpl T, et al. (2000) Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor Nature Medicine. 6: 698-702 |
| Cowan KN, Jones PL, Rabinovitch M. (2000) Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense prevents progression, of vascular disease Journal of Clinical Investigation. 105: 21-34 |
| Cowan KN, Jones PL, Rabinovitch M. (1999) Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin- C, and smooth muscle cell apoptosis Circulation Research. 84: 1223-1233 |
| Cizmeci-Smith G, Asundi V, Stahl R, et al. (1992) Regulated expression of syndecan in vascular smooth muscle cells and cloning of rat syndecan core protein cDNA. Journal of Biological Chemistry. 267: 15729-15736 |