Dennis C. Otero, Ph.D.

Affiliations: 
2001 University of California, San Diego, La Jolla, CA 
Area:
Immunology, Cell Biology
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"Dennis Otero"

Parents

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Robert C. Rickert grad student 2001 UCSD
 (CD19 affects B-cell lymphopoiesis at multiple stages influencing survival, proliferation and differentiation of developing B-cells.)
Linda M Bradley research scientist Sanford Burnham Prebys Medical Discovery Institute (Neurotree)
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Publications

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Hope JL, Otero DC, Bae EA, et al. (2023) PSGL-1 attenuates early TCR signaling to suppress CD8 T cell progenitor differentiation and elicit terminal CD8 T cell exhaustion. Cell Reports. 42: 112436
Hope JL, Zhao M, Stairiker CJ, et al. (2022) MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8 T Cell Responses. Journal of Immunology (Baltimore, Md. : 1950). 208: 603-617
Scortegagna M, Hockemeyer K, Dolgalev I, et al. (2020) Siah2 control of T-regulatory cells limits anti-tumor immunity. Nature Communications. 11: 99
Hope JL, Stairiker CJ, Bae EA, et al. (2019) Striking a Balance-Cellular and Molecular Drivers of Memory T Cell Development and Responses to Chronic Stimulation. Frontiers in Immunology. 10: 1595
Tinoco R, Otero DC, Takahashi AA, et al. (2017) PSGL-1: A New Player in the Immune Checkpoint Landscape. Trends in Immunology
Tinoco R, Carrette F, Barraza ML, et al. (2016) PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 44: 1470
Tinoco R, Carrette F, Barraza ML, et al. (2016) PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 44: 1190-203
Almaden JV, Liu YC, Yang E, et al. (2016) B cell survival and development controlled by the coordination of NFκB family members RelB and cRel. Blood
Otero DC, Fares-Frederickson NJ, Xiao M, et al. (2015) IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling. Journal of Immunology (Baltimore, Md. : 1950). 194: 5120-8
Almaden JV, Tsui R, Liu YC, et al. (2014) A pathway switch directs BAFF signaling to distinct NFκB transcription factors in maturing and proliferating B cells. Cell Reports. 9: 2098-111
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