Alex K. Eapen, Ph.D.

Affiliations: 
2001 University of Iowa, Iowa City, IA 
Area:
Cell Biology
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"Alex Eapen"

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Frederick W. Quelle grad student 2001 University of Iowa
 (Molecular determinants of cytokine -mediated suppression of a DNA damage-induced G1 checkpoint in hematopoietic cells.)
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Publications

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Arlander SJ, Eapen AK, Vroman BT, et al. (2003) Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress. The Journal of Biological Chemistry. 278: 52572-7
Roos-Mattjus P, Vroman BT, Burtelow MA, et al. (2002) Genotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event. The Journal of Biological Chemistry. 277: 43809-12
Eapen AK, Henry MK, Quelle DE, et al. (2001) DNA damage-induced G1 arrest in hematopoietic cells is overridden following phosphatidylinositol 3-kinase-dependent activation of cyclin-dependent kinase 2 Molecular and Cellular Biology. 21: 6113-6121
Henry MK, Lynch JT, Eapen AK, et al. (2001) DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway. Blood. 98: 834-41
Chatterjee TK, Eapen AK, Fisher RA. (1997) A truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of adenylyl cyclase and phosphoinositide phospholipase C Journal of Biological Chemistry. 272: 15481-15487
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