Elizabeth A. Lafleur, Ph.D.

Affiliations: 
2003 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Immunology, Oncology
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"Elizabeth Lafleur"

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Eugenie S. Kleinerman grad student 2003 The University of Texas Graduate School of Biomedical Sciences at Houston
 (IL -12 inhibits the metastatic potential of osteosarcoma cells and induces tumor regression via a mechanism involving Fas /Fas ligand pathway.)
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Publications

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Zhou Z, Lafleur EA, Koshkina NV, et al. (2005) Interleukin-12 up-regulates Fas expression in human osteosarcoma and Ewing's sarcoma cells by enhancing its promoter activity. Molecular Cancer Research : McR. 3: 685-91
Lafleur EA, Koshkina NV, Stewart J, et al. (2004) Increased Fas expression reduces the metastatic potential of human osteosarcoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8114-9
Duan X, Zhou Z, Jia SF, et al. (2004) Interleukin-12 enhances the sensitivity of human osteosarcoma cells to 4-hydroperoxycyclophosphamide by a mechanism involving the Fas/Fas-ligand pathway. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 777-83
Worth LL, Lafleur EA, Jia SF, et al. (2002) Fas expression inversely correlates with metastatic potential in osteosarcoma cells. Oncology Reports. 9: 823-7
Lafleur EA, Jia SF, Worth LL, et al. (2001) Interleukin (IL)-12 and IL-12 gene transfer up-regulate Fas expression in human osteosarcoma and breast cancer cells. Cancer Research. 61: 4066-71
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