Anita K. Iyer, Ph.D.

Affiliations: 
2006 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Genetics
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"Anita Iyer"

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Edward R. B. McCabe grad student 2006 UCLA
 (Molecular mechanisms of DAX1 (NR0B1) and SHP (NR0B2) action: Homodimerization of unusual members of the nuclear receptor superfamily.)
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Publications

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Huang PP, Brusman LE, Iyer AK, et al. (2016) A Novel Gonadotropin-Releasing Hormone 1 (Gnrh1) Enhancer-Derived Noncoding RNA Regulates Gnrh1 Gene Expression in GnRH Neuronal Cell Models. Plos One. 11: e0158597
Glidewell-Kenney CA, Shao PP, Iyer AK, et al. (2013) Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. Molecular Endocrinology (Baltimore, Md.). 27: 437-54
Beneduzzi D, Iyer AK, Trarbach EB, et al. (2011) Mutational analysis of the necdin gene in patients with congenital isolated hypogonadotropic hypogonadism. European Journal of Endocrinology / European Federation of Endocrine Societies. 165: 145-50
Iyer AK, Brayman MJ, Mellon PL. (2011) Dynamic chromatin modifications control GnRH gene expression during neuronal differentiation and protein kinase C signal transduction. Molecular Endocrinology (Baltimore, Md.). 25: 460-73
Iyer AK, Miller NL, Yip K, et al. (2010) Enhancers of GnRH transcription embedded in an upstream gene use homeodomain proteins to specify hypothalamic expression. Molecular Endocrinology (Baltimore, Md.). 24: 1949-64
Kinsey M, Smith R, Iyer AK, et al. (2009) EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma. Cancer Research. 69: 9047-55
Iyer AK, Zhang YH, McCabe ER. (2007) LXXLL motifs and AF-2 domain mediate SHP (NR0B2) homodimerization and DAX1 (NR0B1)-DAX1A heterodimerization. Molecular Genetics and Metabolism. 92: 151-9
Iyer AK, Zhang YH, McCabe ER. (2006) Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers. Molecular Endocrinology (Baltimore, Md.). 20: 2326-42
Iyer AK, McCabe ER. (2004) Molecular mechanisms of DAX1 action. Molecular Genetics and Metabolism. 83: 60-73
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