Randall L. Evans, Ph.D.
Affiliations: | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Molecular Biology, OncologyGoogle:
"Randall Evans"Parents
Sign in to add mentorJim Klostergaard | grad student | 2002 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
(Structural and functional analysis of p84N5.) |
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Publications
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Khodadadian M, Leroux ME, Auzenne E, et al. (2009) MRP- and BCL-2-mediated drug resistance in human SCLC: Effects of apoptotic sphingolipids in vitro Lung Cancer. 66: 48-57 |
Zhang W, Konopleva M, Ruvolo VR, et al. (2008) Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway Leukemia. 22: 808-818 |
Leroux ME, Auzenne E, Evans R, et al. (2007) Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells. The Prostate. 67: 1699-1717 |
Carter BZ, Mak DH, Schober WD, et al. (2006) Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells. Blood. 108: 630-7 |
Samudio I, Konopleva M, Pelicano H, et al. (2006) A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: Direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis Molecular Pharmacology. 69: 1182-1193 |
Samudio I, Konopleva M, Hail N, et al. (2005) 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer. The Journal of Biological Chemistry. 280: 36273-82 |
Samudio I, Konopleva M, Pelicano H, et al. (2005) A Novel Mechanism of Action of Methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate (CDDO-Me): Direct Permeabilization of the Inner Mitochondrial Membrane To Inhibit Electron Transport and Induce Apoptosis. Blood. 106: 4462-4462 |
Zeng Z, Evans RL, Huang Z, et al. (2004) CXCR4 Inhibition as a Therapeutic Strategy in Leukemia. Blood. 104: 456-456 |
Carter BZ, Schober WD, McQueen T, et al. (2004) Triptolide-Induced Apoptosis Is Dependent on Caspase Activation and NFκB Signaling and Mediated by XIAP and Survivin Downregulation through the Mitochondrial Pathway in Leukemic Cells. Blood. 104: 3394-3394 |
Ananthaswamy HN, Ouhtit A, Evans RL, et al. (1999) Persistence of p53 mutations and resistance of keratinocytes to apoptosis are associated with the increased susceptibility of mice lacking the XPC gene to UV carcinogenesis. Oncogene. 18: 7395-8 |