Dakun Wang, Ph.D.

Affiliations: 
2004 University of Rochester, Rochester, NY 
Area:
Oncology, Pathology
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"Dakun Wang"

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Edward M. Messing grad student 2004 Rochester
 (Two novel MET -interacting proteins, RanBP9 and RanBP10, share high sequence similarity, but differ in their effects on Ras -Erk signaling.)
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Publications

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Gaur K, Li J, Wang D, et al. (2013) The Birt-Hogg-Dubé tumor suppressor Folliculin negatively regulates ribosomal RNA synthesis. Human Molecular Genetics. 22: 284-99
Li Z, Wang D, Messing EM, et al. (2005) VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha. Embo Reports. 6: 373-8
Wang D, Li Z, Messing EM, et al. (2005) The SPRY domain-containing SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. The Journal of Biological Chemistry. 280: 16393-401
Wang D, Li Z, Schoen SR, et al. (2004) A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling. Biochemical and Biophysical Research Communications. 313: 320-6
Li Z, Wang D, Na X, et al. (2003) The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity. The Embo Journal. 22: 1857-67
Wang D, Li Z, Messing EM, et al. (2002) Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM. The Journal of Biological Chemistry. 277: 36216-22
Li Z, Wang D, Na X, et al. (2002) Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor. Biochemical and Biophysical Research Communications. 294: 700-9
Li Z, Na X, Wang D, et al. (2002) Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein. The Journal of Biological Chemistry. 277: 4656-62
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