Kan Liu, Ph.D.
Affiliations: | 2001 | University of Alabama, Birmingham, Birmingham, AL, United States |
Area:
Cell BiologyGoogle:
"Kan Liu"Parents
Sign in to add mentor| Jeffrey E. Kudlow | grad student | 2001 | UAB | |
| (The roles of protein O-GlcNAc in pancreatic beta-cell apoptosis and hormone secretion.) | ||||
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| Roh M, Paterson AJ, Liu K, et al. (2005) Proteolytic processing of TGFalpha redirects its mitogenic activity: the membrane-anchored form is autocrine, the secreted form is paracrine. Biochimica Et Biophysica Acta. 1743: 231-42 |
| Liu K, Paterson AJ, Zhang F, et al. (2004) Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism. Journal of Neurochemistry. 89: 1044-55 |
| Liu K, Paterson AJ, Konrad RJ, et al. (2002) Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion. Molecular and Cellular Endocrinology. 194: 135-46 |
| Konrad RJ, Mikolaenko I, Tolar JF, et al. (2001) The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase. The Biochemical Journal. 356: 31-41 |
| Konrad RJ, Liu K, Kudlow JE. (2000) A modified method of islet isolation preserves the ability of pancreatic islets to increase protein O-glycosylation in response to glucose and streptozotocin. Archives of Biochemistry and Biophysics. 381: 92-8 |
| Liu K, Paterson AJ, Chin E, et al. (2000) Glucose stimulates protein modification by O-linked GlcNAc in pancreatic cells: Linkage of O-linked GlcNAc to β cell death Proceedings of the National Academy of Sciences of the United States of America. 97: 2820-2825 |