Frank O. Bartel, Ph.D.

Affiliations: 
2006 Medical University of South Carolina, Charleston, SC, United States 
Area:
Genetics, Molecular Biology
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"Frank Bartel"

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Demetri D. Spyropoulos grad student 2006 MUSC
 (Generation and characterization of an allelic series of Ets1 gene targeted mice: Thymomegaly, microsplenia and defective homeostatic proliferation of peripheral lymphocytes of Ets1DeltaVII but not Ets1S->A mice.)
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Publications

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Bauer M, Kantelhardt EJ, Stiewe T, et al. (2019) Specific allelic variants of SNPs in the and genes are associated with earlier tumor onset and progression in Caucasian breast cancer patients. Oncotarget. 10: 1975-1992
Vogiatzi F, Brandt DT, Schneikert J, et al. (2016) Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5. Proceedings of the National Academy of Sciences of the United States of America
Zhang P, Elabd S, Hammer S, et al. (2015) TRIM25 has a dual function in the p53/Mdm2 circuit. Oncogene
Groß S, Immel UD, Klintschar M, et al. (2014) Germline genetics of the p53 pathway affect longevity in a gender specific manner. Current Aging Science. 7: 91-100
Bartel F, Balschun K, Gradhand E, et al. (2012) Inverse expression of cystein-rich 61 (Cyr61/CCN1) and connective tissue growth factor (CTGF/CCN2) in borderline tumors and carcinomas of the ovary. International Journal of Gynecological Pathology. 31: 405-415
Lenos K, Grawenda AM, Lodder K, et al. (2012) Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer. Cancer Research. 72: 4074-84
Wynendaele J, Böhnke A, Leucci E, et al. (2010) An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity. Cancer Research. 70: 9641-9
Phillips A, Teunisse A, Lam S, et al. (2010) HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity Journal of Biological Chemistry. 285: 29111-29127
Boehnke A, Wynendale J, Lambertz I, et al. (2010) Abstract 2841: A SNP in the 3′-UTR of the MDMX gene is strongly correlated with decreased overall and disease-free survival in ovarian carcinoma patients in an estrogen-receptor-dependent manner Cancer Research. 70: 2841-2841
Atwal GS, Kirchhoff T, Bond EE, et al. (2009) Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene. Proceedings of the National Academy of Sciences of the United States of America. 106: 10236-41
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