M. K. Conley-LaComb, Ph.D.

Affiliations: 
2010 Cancer Biology Wayne State University, Detroit, MI, United States 
Area:
Cell Biology, Oncology, Molecular Biology
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"M. Conley-LaComb"

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Hyeong-Reh C. Kim grad student 2010 Wayne State
 (Matriptase/PDGF D/beta-PDGFR signaling axis in human prostate cancer: The role of PTEN in the regulation of PDGF D expression.)
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Publications

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Conley-LaComb MK, Semaan L, Singareddy R, et al. (2016) Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis. Molecular Cancer. 15: 68
Powell K, Semaan L, Conley-LaComb MK, et al. (2015) ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer Cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2569-79
Singareddy R, Semaan L, Conley-Lacomb MK, et al. (2013) Transcriptional regulation of CXCR4 in prostate cancer: significance of TMPRSS2-ERG fusions. Molecular Cancer Research : McR. 11: 1349-61
Conley-LaComb MK, Saliganan A, Kandagatla P, et al. (2013) PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling. Molecular Cancer. 12: 85
St John J, Powell K, Conley-Lacomb MK, et al. (2012) TMPRSS2-ERG Fusion Gene Expression in Prostate Tumor Cells and Its Clinical and Biological Significance in Prostate Cancer Progression. Journal of Cancer Science & Therapy. 4: 94-101
Najy AJ, Jung YS, Won JJ, et al. (2012) Cediranib inhibits both the intraosseous growth of PDGF D-positive prostate cancer cells and the associated bone reaction. The Prostate. 72: 1328-38
Conley-LaComb MK, Huang W, Wang S, et al. (2012) PTEN regulates PDGF ligand switch for β-PDGFR signaling in prostate cancer. The American Journal of Pathology. 180: 1017-27
Ustach CV, Huang W, Conley-LaComb MK, et al. (2010) A novel signaling axis of matriptase/PDGF-D/ß-PDGFR in human prostate cancer. Cancer Research. 70: 9631-40
Kim S, Huang W, Mottillo EP, et al. (2010) Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP. Biochimica Et Biophysica Acta. 1803: 1287-97
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