Karl J. Clark, Ph.D.

Affiliations: 
1990-1994 Biology/Chemistry University of Wisconsin-Eau Claire, Eau Claire, WI, United States 
 1995-2003 Molecular, Cellular, Developmental Biology and Genetics University of Minnesota, Twin Cities, Minneapolis, MN 
 2004-2007 Animal Science University of Minnesota, Twin Cities, Minneapolis, MN 
 2008- Biochemistry and Molecular Biology Mayo Clinic, Rochester, MN, United States 
Area:
Genetics, Molecular Biology, Behavior, Gene Editing
Website:
https://www.mayo.edu/research/faculty/clark-karl-j-ph-d/bio-00096400
Google:
"Karl Clark"

Parents

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Scott C. Hartsel research assistant 1993-1994 UW-Eau Claire
 (Antimicrobial peptides, including PGLA)
Perry B. Hackett grad student 2003 UMN
 (The development of Sleeping Beauty gene -trap transposons for insertional mutagenesis of vertebrates.)
Scott C. Fahrenkrug post-doc 2004-2007 UMN
 (Transposon and recombinase applications in livestock.)
Stephen C. Ekker post-doc 2007-2011 Mayo Clinic (Neurotree)
 (Functional genetics in zebrafish)

Children

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Randall G. Krug grad student 2012-2017 Mayo Clinic
Han B. Lee grad student 2013-2018 Mayo Clinic
Soaleha Shams post-doc 2021-2023 (Neurotree)
BETA: Related publications

Publications

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Lee H, Shams S, Thi VHD, et al. (2023) The canonical HPA axis facilitates and maintains light adaptive behavior. Research Square
Kar B, Castillo SR, Sabharwal A, et al. (2023) Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities. International Journal of Molecular Sciences. 24
Sabharwal A, Wishman MD, Cervera RL, et al. (2022) Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality. Elife. 11
Ding Y, Lang D, Yan J, et al. (2022) A phenotype-based forward genetic screen identifies as a sick sinus syndrome gene. Elife. 11
Sabharwal A, Campbell JM, Schwab TL, et al. (2022) A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish. Genes. 13
Liu F, Kambakam S, Almeida MP, et al. (2022) Cre/ regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration. Elife. 11
Kar B, Sabharwal A, Restrepo-Castillo S, et al. (2022) An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines. Star Protocols. 3: 101288
Simone BW, Lee HB, Daby CL, et al. (2021) Chimeric RNA:DNA TracrRNA Improves Homology-Directed Repair and . The Crispr Journal
Sabharwal A, Kar B, Restrepo-Castillo S, et al. (2021) The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells and Zebrafish Disease Models . The Crispr Journal. 4: 799-821
Welker JM, Wierson WA, Almeida MP, et al. (2021) GeneWeld: Efficient Targeted Integration Directed by Short Homology in Zebrafish. Bio-Protocol. 11: e4100
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