Kelly M. McGarvey, Ph.D.

Affiliations: 
2008 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Oncology
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"Kelly McGarvey"

Parents

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Stephen B. Baylin grad student 2008 Johns Hopkins
 (DNA methylation and histone modifications: Connections in a cancer setting.)
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Publications

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Morales J, Pujar S, Loveland JE, et al. (2022) A joint NCBI and EMBL-EBI transcript set for clinical genomics and research. Nature. 604: 310-315
Balmer P, Bauer A, Pujar S, et al. (2017) A curated catalog of canine and equine keratin genes. Plos One. 12: e0180359
Mohammad HP, Cai Y, McGarvey KM, et al. (2009) Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation. Cancer Research. 69: 6322-30
Tiwari VK, McGarvey KM, Licchesi JD, et al. (2008) PcG proteins, DNA methylation, and gene repression by chromatin looping. Plos Biology. 6: 2911-27
McGarvey KM, Van Neste L, Cope L, et al. (2008) Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells. Cancer Research. 68: 5753-9
Tiwari VK, Cope L, McGarvey KM, et al. (2008) A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations. Genome Research. 18: 1171-9
McGarvey KM, Greene E, Fahrner JA, et al. (2007) DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2. Cancer Research. 67: 5097-102
Ohm JE, McGarvey KM, Yu X, et al. (2007) A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nature Genetics. 39: 237-42
Ting AH, McGarvey KM, Baylin SB. (2006) The cancer epigenome--components and functional correlates. Genes & Development. 20: 3215-31
Pruitt K, Zinn RL, Ohm JE, et al. (2006) Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. Plos Genetics. 2: e40
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