Xiao-Chun Xu, Ph.D.

Affiliations: 
2001 Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Cell Biology, Molecular Biology
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"Xiao-Chun Xu"

Parents

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Thalachallour Mohanakumar grad student 2001 Washington University
 (Molecular and cellular mechanisms for human anti-porcine xenoreactive immune responses.)
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Publications

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Ramachandran S, Jaramillo A, Xu XC, et al. (2004) Human immune responses to porcine endogenous retrovirus-derived peptides presented naturally in the context of porcine and human major histocompatibility complex class I molecules: implications in xenotransplantation of porcine organs. Transplantation. 77: 1580-8
McKane BW, Ramachandran S, Xu XC, et al. (2004) Natural antibodies prevent in vivo transmission of porcine islet-derived endogenous retrovirus to human cells. Cell Transplantation. 13: 137-43
McKane BW, Ramachandran S, Yang J, et al. (2003) Xenoreactive anti-Galalpha(1,3)Gal antibodies prevent porcine endogenous retrovirus infection of human in vivo. Human Immunology. 64: 708-17
Xu XC, Goodman J, Sasaki H, et al. (2002) Activation of natural killer cells and macrophages by porcine endothelial cells augments specific T-cell xenoresponse. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 314-22
Xu XC, Howard T, Mohanakumar T. (2001) Tissue-specific peptides influence human T cell repertoire to porcine xenoantigens. Transplantation. 72: 1205-12
Mohanakumar T, Xu XC, Jaramillo A. (2000) Regulation of xeno-reactive CD4+ T cells by CD8+CD28- T suppressor cells. Transplantation. 69: 1233-4
Sasaki H, Xu X, Naziruddin B, et al. (2000) A NONCLASSICAL CLASS I SWINE LEUKOCYTE ANTIGEN (PD-6) FUNCTION AS A NOVEL PORCINE NATURAL KILLER CELL INHIBITORY MOLECULE. Transplantation. 69: S384
Xu X, Sasaki H, Howard T, et al. (2000) PORCINE ENDOTHELIAL CELLS INDUCED IFN-GAMMA PRODUCTION IN HUMAN NATURAL KILLER CELLS THROUGH IL-12-DEPENDENT AND -INDEPENDENT PATHWAYS. Transplantation. 69: S248
Sasaki H, Xu XC, Mohanakumar T. (1999) HLA-E and HLA-G expression on porcine endothelial cells inhibit xenoreactive human NK cells through CD94/NKG2-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 163: 6301-5
Chen M, Xu XC, Wu WS, et al. (1999) Analysis of variable region of T-cell receptor beta chain usage in the human anti-porcine xenoresponse. Transplantation. 68: 586-9
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