Jennifer Antonchuk, Ph.D.

Affiliations: 
2002 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Genetics, Molecular Biology, Cell Biology
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"Jennifer Antonchuk"

Parents

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Keith Humphries grad student 2002 UBC
 (Functional analysis of the homeobox gene HOXB4 in primitive hematopoietic cells.)
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Publications

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Souilhol C, Gonneau C, Lendinez JG, et al. (2016) Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells. Nature Communications. 7: 10784
Antonchuk J. (2013) Formation of embryoid bodies from human pluripotent stem cells using AggreWell™ plates. Methods in Molecular Biology (Clifton, N.J.). 946: 523-33
Thorén LA, Liuba K, Bryder D, et al. (2008) Kit regulates maintenance of quiescent hematopoietic stem cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 2045-53
Qian H, Buza-Vidas N, Hyland CD, et al. (2007) Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells. Cell Stem Cell. 1: 671-84
Buza-Vidas N, Antonchuk J, Qian H, et al. (2006) Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK. Genes & Development. 20: 2018-23
Antonchuk J, Hyland CD, Hilton DJ, et al. (2004) Synergistic effects on erythropoiesis, thrombopoiesis, and stem cell competitiveness in mice deficient in thrombopoietin and steel factor receptors. Blood. 104: 1306-13
Helgason CD, Antonchuk J, Bodner C, et al. (2003) Homeostasis and regeneration of the hematopoietic stem cell pool are altered in SHIP-deficient mice. Blood. 102: 3541-7
Kalberer CP, Antonchuk J, Keith Humphries R. (2002) Genetic modification of murine hematopoietic stem cells by retroviruses. Methods in Molecular Medicine. 63: 231-42
Miller CL, Imren S, Antonchuk J, et al. (2002) Feasibility of using autologous transplantation to evaluate hematopoietic stem cell-based gene therapy strategies in transgenic mouse models of human disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 422-8
Antonchuk J, Sauvageau G, Humphries RK. (2002) HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 109: 39-45
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