Vedurmudi A. Rao, Ph.D.
Affiliations: | 2003 | The University of Texas Graduate School of Biomedical Sciences at Houston |
Area:
Pharmacology, Molecular Biology, Cell BiologyGoogle:
"Vedurmudi Rao"Parents
Sign in to add mentor| William Plunkett | grad student | 2003 | The University of Texas Graduate School of Biomedical Sciences at Houston | |
| (Mechanism of damage sensing and cell killing following the inhibition of nucleotide excision repair by fludarabine in quiescent cells.) | ||||
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Publications
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| Nakamura AJ, Rao VA, Pommier Y, et al. (2010) The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks. Cell Cycle (Georgetown, Tex.). 9: 389-97 |
| Sordet O, Goldman A, Redon C, et al. (2008) Topoisomerase I requirement for death receptor-induced apoptotic nuclear fission. The Journal of Biological Chemistry. 283: 23200-8 |
| Shimura T, Torres MJ, Martin MM, et al. (2008) Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress. Journal of Molecular Biology. 375: 1152-64 |
| Rao VA, Agama K, Holbeck S, et al. (2007) Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. Cancer Research. 67: 9971-9 |
| Rao VA, Conti C, Guirouilh-Barbat J, et al. (2007) Endogenous γ-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase-deficient cells is related to DNA replication arrested forks Molecular Cancer Research. 5: 713-724 |
| Takemura H, Rao VA, Sordet O, et al. (2006) Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks. The Journal of Biological Chemistry. 281: 30814-23 |
| Pommier Y, Barcelo JM, Rao VA, et al. (2006) Repair of topoisomerase I-mediated DNA damage. Progress in Nucleic Acid Research and Molecular Biology. 81: 179-229 |
| Rao VA, Fan AM, Meng L, et al. (2005) Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage. Molecular and Cellular Biology. 25: 8925-37 |
| Pommier Y, Sordet O, Rao VA, et al. (2005) Targeting chk2 kinase: molecular interaction maps and therapeutic rationale. Current Pharmaceutical Design. 11: 2855-72 |
| Sampath D, Rao VA, Plunkett W. (2003) Mechanisms of apoptosis induction by nucleoside analogs. Oncogene. 22: 9063-74 |