Xian M. O'Brien, Ph.D.
Affiliations: | 2010 | Brown University, Providence, RI |
Area:
Cell BiologyGoogle:
"Xian O'Brien"Parents
Sign in to add mentor| Jonathan Reichner | grad student | 2010 | Brown | |
| (Innate immune functions of human polymorphonuclear leukocytes as mediated by the beta2 integrin, CR3, and modulated by beta-glucan, a fungal pathogen associated molecular pattern.) | ||||
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| Dickinson CM, LeBlanc BW, Edhi MM, et al. (2018) Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients. Journal of Intensive Care. 6: 19 |
| Johnson CM, O'Brien XM, Byrd AS, et al. (2016) Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal β-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response. Journal of Immunology (Baltimore, Md. : 1950) |
| O'Brien XM, Biron BM, Reichner JS. (2016) Consequences of extracellular trap formation in sepsis. Current Opinion in Hematology |
| O'Brien XM, Reichner JS. (2016) Neutrophil Integrins and Matrix Ligands and NET Release. Frontiers in Immunology. 7: 363 |
| Biron BM, Chung CS, O'Brien XM, et al. (2016) Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model. Journal of Innate Immunity |
| Byrd AS, O'Brien XM, Laforce-Nesbitt SS, et al. (2015) NETosis in Neonates: Evidence of a Reactive Oxygen Species-Independent Pathway in Response to Fungal Challenge. The Journal of Infectious Diseases |
| Loosley AJ, O'Brien XM, Reichner JS, et al. (2015) Describing directional cell migration with a characteristic directionality time. Plos One. 10: e0127425 |
| O'Brien XM, Loosley AJ, Oakley KE, et al. (2014) Technical advance: introducing a novel metric, directionality time, to quantify human neutrophil chemotaxis as a function of matrix composition and stiffness. Journal of Leukocyte Biology. 95: 993-1004 |
| Loosley AJ, O'Brien XM, Reichner JS, et al. (2014) Quantification of Directional Migration by a Characteristic Directionality Time Biophysical Journal. 106: 573a |
| Byrd AS, O'Brien XM, Johnson CM, et al. (2013) An extracellular matrix-based mechanism of rapid neutrophil extracellular trap formation in response to Candida albicans. Journal of Immunology (Baltimore, Md. : 1950). 190: 4136-48 |