Eunice Y. Chen, Ph.D.

Affiliations: 
2001 Stanford University, Palo Alto, CA 
Area:
Oncology, Cell Biology, Animal Physiology Biology
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"Eunice Chen"

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Amato J. Giaccia grad student 2001 Stanford
 (Hypoxia -induced signaling pathways.)
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Publications

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Laderoute K, Calaoagan J, Mendonca H, et al. (2012) Early responses of SiHa human squamous carcinoma cells to hypoxic signals. International Journal of Oncology. 8: 875-82
Le QT, Chen E, Salim A, et al. (2006) An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1507-14
Le QT, Shi G, Cao H, et al. (2005) Galectin-1: a link between tumor hypoxia and tumor immune privilege. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 8932-41
Chen Y, Shi G, Xia W, et al. (2004) Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. Cancer Research. 64: 7302-10
Chen EY, Mazure NM, Cooper JA, et al. (2001) Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer Research. 61: 2429-33
Laderoute KR, Alarcon RM, Brody MD, et al. (2000) Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 2941-50
Zundel W, Schindler C, Haas-Kogan D, et al. (2000) Loss of PTEN facilitates HIF-1-mediated gene expression. Genes & Development. 14: 391-6
Chen EY, Fujinaga M, Giaccia AJ. (1999) Hypoxic microenvironment within an embryo induces apoptosis and is essential for proper morphological development. Teratology. 60: 215-25
Mazure NM, Chen EY, Laderoute KR, et al. (1997) Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood. 90: 3322-31
Mazure NM, Chen EY, Yeh P, et al. (1996) Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression. Cancer Research. 56: 3436-40
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