Cheryl J. Buckholz, Ph.D.

Affiliations: 
2003 Oregon State University, Corvallis, OR 
Area:
Pharmacology
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"Cheryl Buckholz"

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Rosita J. Rodriguez grad student 2003 Oregon State
 (Acute bioactivation and hepatotoxicity of ketoconazole in rat and the determinant presence of flavin -containing monooxygenase (FMO) isoforms in human duodenum, jejunum, ileum, and colon microsomes and Caco-2 cell line.)
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Publications

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Rodriguez RJ, Buckholz CJ. (2003) Hepatotoxicity of ketoconazole in Sprague-Dawley rats: Glutathione depletion, flavin-containing monooxygenases-mediated bioactivation and hepatic covalent binding Xenobiotica. 33: 429-441
Rodriguez RJ, Proteau PJ, Marquez BL, et al. (1999) Flavin-containing monooxygenase-mediated metabolism of N-deacetyl ketoconazole by rat hepatic microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 27: 880-6
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