Benjamin E. Deverman, Ph.D.
Affiliations: | 2002 | Washington University, Saint Louis, St. Louis, MO |
Area:
Molecular Biology, Cell Biology, OncologyGoogle:
"Benjamin Deverman"Parents
Sign in to add mentor| Steven J. Weintraub | grad student | 2002 | Washington University | |
| (Bcl-x(L) deamidation is a critical switch in the regulation of the response to DNA damage.) | ||||
Children
Sign in to add trainee| Cynthia S Moncada-Reid | research assistant | 2018-2019 | Broad Institute (MIT/Harvard) (Neurotree) |
| Lia R D'Alessandro | research assistant | 2022-2024 | Broad Institute (Neurotree) |
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Publications
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| Huang Q, Chen AT, Chan KY, et al. (2023) Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier. Plos Biology. 21: e3002112 |
| Ravindra Kumar S, Miles TF, Chen X, et al. (2020) Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types. Nature Methods |
| Zeng J, Wang Y, Luo Z, et al. (2019) TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice. Cell Reports. 27: 549-560.e6 |
| Challis RC, Ravindra Kumar S, Chan KY, et al. (2019) Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nature Protocols |
| Deverman BE, Ravina BM, Bankiewicz KS, et al. (2018) Gene therapy for neurological disorders: progress and prospects. Nature Reviews. Drug Discovery |
| Bedbrook CN, Deverman BE, Gradinaru V. (2018) Viral Strategies for Targeting the Central and Peripheral Nervous Systems. Annual Review of Neuroscience |
| Chan KY, Jang MJ, Yoo BB, et al. (2017) Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems. Nature Neuroscience |
| Deverman BE, Pravdo PL, Simpson BP, et al. (2016) Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature Biotechnology |
| Farshim PP, Deverman BE, Bates GP. (2016) L3 Systemic administration of a novel AAV variant results in widespread and efficient gene transfer in R6/2 mice Journal of Neurology, Neurosurgery & Psychiatry. 87: A91.1-A91 |
| Deverman BE, Pravdo PL, Simpson BP, et al. (2016) 252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System Molecular Therapy. 24: S99 |