John E. Le Lay, Ph.D.
Affiliations: | 2004 | Vanderbilt University, Nashville, TN |
Area:
Molecular BiologyGoogle:
"John Le Lay"Parents
Sign in to add mentor| Roland Stein | grad student | 2004 | Vanderbilt | |
| (Investigations into islet-selective gene transcription: Insulin-like growth factor II mRNA -binding proteins and the regulation of human insulin gene expression by PDX-1.) | ||||
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Publications
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| Kim JH, Hedrick S, Tsai WW, et al. (2017) CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America |
| Luan B, Yoon YS, Le Lay J, et al. (2015) CREB pathway links PGE2 signaling with macrophage polarization. Proceedings of the National Academy of Sciences of the United States of America |
| Bernstein DL, Le Lay JE, Ruano EG, et al. (2015) TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts. The Journal of Clinical Investigation. 125: 1998-2006 |
| Shin S, Le Lay J, Everett LJ, et al. (2014) CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells. Molecular Metabolism. 3: 803-12 |
| Lee D, Le Lay J, Kaestner KH. (2014) The transcription factor CREB has no non-redundant functions in hepatic glucose metabolism in mice. Diabetologia. 57: 1242-8 |
| Jiao Y, Le Lay J, Yu M, et al. (2014) Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting. Diabetes. 63: 1283-8 |
| Jiao Y, Rieck S, Le Lay J, et al. (2013) CISH has no non-redundant functions in glucose homeostasis or beta cell proliferation during pregnancy in mice. Diabetologia. 56: 2435-45 |
| Everett LJ, Le Lay J, Lukovac S, et al. (2013) Integrative genomic analysis of CREB defines a critical role for transcription factor networks in mediating the fed/fasted switch in liver. Bmc Genomics. 14: 337 |
| Miller RA, Chu Q, Le Lay J, et al. (2011) Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. The Journal of Clinical Investigation. 121: 2518-28 |
| Gao Y, Schug J, McKenna LB, et al. (2011) Tissue-specific regulation of mouse microRNA genes in endoderm-derived tissues. Nucleic Acids Research. 39: 454-63 |