Rajeev M. Mahimkar, Ph.D.

Affiliations: 
2000 Tulane University, New Orleans, LA, United States 
Area:
General Biology, Animal Physiology Biology, Molecular Biology
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"Rajeev Mahimkar"

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William Baricos grad student 2000 Tulane
 (Identification, cellular distribution and potential function of MDC9 in rat kidney.)
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Ceron CS, Baligand C, Joshi SK, et al. (2017) An Intracellular Matrix Metalloproteinase-2 Isoform Induces Tubular Regulated Necrosis: Implications for Acute Kidney Injury. American Journal of Physiology. Renal Physiology. ajprenal.00461.2016
Lovett DH, Mahimkar R, Raffai RL, et al. (2013) N-terminal truncated intracellular matrix metalloproteinase-2 induces cardiomyocyte hypertrophy, inflammation and systolic heart failure. Plos One. 8: e68154
Lovett DH, Mahimkar R, Raffai RL, et al. (2012) A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity. Plos One. 7
Mahimkar R, Alfonso-Jaume MA, Cape LM, et al. (2011) Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype. Carcinogenesis. 32: 1806-1814
Mahimkar R, Nguyen A, Mann M, et al. (2009) Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 18: 253-61
Bergman MR, Teerlink JR, Mahimkar R, et al. (2007) Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1847-60
Cheng S, Pollock AS, Mahimkar R, et al. (2006) Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1898-900
Alfonso-Jaume MA, Bergman MR, Mahimkar R, et al. (2006) Cardiac ischemia-reperfusion injury induces matrix metalloproteinase-2 expression through the AP-1 components FosB and JunB. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1838-46
Lee JG, Dahi S, Mahimkar R, et al. (2005) Intronic regulation of matrix metalloproteinase-2 revealed by in vivo transcriptional analysis in ischemia. Proceedings of the National Academy of Sciences of the United States of America. 102: 16345-50
Mahimkar RM, Visaya O, Pollock AS, et al. (2005) The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins. The Biochemical Journal. 385: 461-8
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