Buxin Chen, Ph.D.

Affiliations: 
2008 Georgia Institute of Technology, Atlanta, GA 
Area:
Genetics
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"Buxin Chen"

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Yury O. Chernoff grad student 2008 Georgia Tech
 (Prion species barrier at the short phylogenetic distances in the yeast model.)
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Publications

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Sharma A, Bruce KL, Chen B, et al. (2015) Contributions of the Prion Protein Sequence, Strain and Environment to the Species Barrier. The Journal of Biological Chemistry
Soto AG, Smith TH, Chen B, et al. (2015) N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias. Proceedings of the National Academy of Sciences of the United States of America
Chen B, Soto AG, Coronel LJ, et al. (2015) Characterization of thrombin-bound dabigatran effects on protease-activated receptor-1 expression and signaling in vitro. Molecular Pharmacology. 88: 95-105
Chen B, Siderovski DP, Neubig RR, et al. (2014) Regulation of protease-activated receptor 1 signaling by the adaptor protein complex 2 and R4 subfamily of regulator of G protein signaling proteins. The Journal of Biological Chemistry. 289: 1580-91
Dores MR, Chen B, Lin H, et al. (2012) ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting. The Journal of Cell Biology. 197: 407-19
Chen B, Dores MR, Grimsey N, et al. (2011) Adaptor protein complex-2 (AP-2) and epsin-1 mediate protease-activated receptor-1 internalization via phosphorylation- and ubiquitination-dependent sorting signals. The Journal of Biological Chemistry. 286: 40760-70
Chen B, Bruce KL, Newnam GP, et al. (2010) Genetic and epigenetic control of the efficiency and fidelity of cross-species prion transmission. Molecular Microbiology. 76: 1483-99
Soh UJ, Dores MR, Chen B, et al. (2010) Signal transduction by protease-activated receptors. British Journal of Pharmacology. 160: 191-203
Yeh V, Broering JM, Romanyuk A, et al. (2010) The Hofmeister effect on amyloid formation using yeast prion protein. Protein Science : a Publication of the Protein Society. 19: 47-56
Chen B, Newnam GP, Chernoff YO. (2007) Prion species barrier between the closely related yeast proteins is detected despite coaggregation. Proceedings of the National Academy of Sciences of the United States of America. 104: 2791-6
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