Lefteris C. Zacharia, Ph.D.

Affiliations: 
2002 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacology, Animal Physiology Biology
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"Lefteris Zacharia"

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Edwin K. Jackson grad student 2002 University of Pittsburgh
 (Protective role of the 2 -hydroxyestradiol methylation pathway in the cardiovascular and renal systems: Interaction with catecholamines.)
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Choukèr A, Ohta A, Martignoni A, et al. (2012) In vivo hypoxic preconditioning protects from warm liver ischemia-reperfusion injury through the adenosine A2B receptor. Transplantation. 94: 894-902
Dubey RK, Jackson EK, Gillespie DG, et al. (2010) Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells. The Journal of Clinical Endocrinology and Metabolism. 95: E9-17
Su Y, Huang X, Raskovalova T, et al. (2008) Cooperation of adenosine and prostaglandin E2 (PGE2) in amplification of cAMP-PKA signaling and immunosuppression. Cancer Immunology, Immunotherapy : Cii. 57: 1611-23
Dubey RK, Jackson EK, Gillespie DG, et al. (2008) Medroxyprogesterone abrogates the inhibitory effects of estradiol on vascular smooth muscle cells by preventing estradiol metabolism. Hypertension. 51: 1197-202
Jackson EK, Gillespie DG, Zhu C, et al. (2008) Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. Hypertension. 51: 719-26
Funakoshi H, Zacharia LC, Tang Z, et al. (2007) A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction. Circulation. 115: 2307-15
Jackson EK, Mi Z, Zacharia LC, et al. (2007) The pancreatohepatorenal cAMP-adenosine mechanism. The Journal of Pharmacology and Experimental Therapeutics. 321: 799-809
Jackson EK, Ren J, Zacharia LC, et al. (2007) Characterization of renal ecto-phosphodiesterase. The Journal of Pharmacology and Experimental Therapeutics. 321: 810-5
Zacharia LC, Jackson EK, Kloosterboer HJ, et al. (2006) Conversion of tibolone to 7alpha-methyl-ethinyl estradiol using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry: interpretation and clinical implications. Menopause (New York, N.Y.). 13: 926-34
Arendash GW, Schleif W, Rezai-Zadeh K, et al. (2006) Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. Neuroscience. 142: 941-52
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