Irene Jarchum, Ph.D.
Affiliations: | 2009 | Yeshiva University, New York, NY, United States |
Area:
ImmunologyGoogle:
"Irene Jarchum"Parents
Sign in to add mentor| Teresa P. DiLorenzo | grad student | 2009 | Yeshiva University | |
| (A study of T cell antigens relevant to autoimmune diabetes in mice and humans.) | ||||
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Publications
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| Antal Z, Baker JC, Smith C, et al. (2012) Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes. Journal of Immunology (Baltimore, Md. : 1950). 188: 5766-75 |
| Brims DR, Qian J, Jarchum I, et al. (2010) Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. International Immunology. 22: 191-203 |
| Jarchum I, DiLorenzo TP. (2010) Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin. Journal of Immunology (Baltimore, Md. : 1950). 184: 658-65 |
| Gao HX, Campbell SR, Burkly LC, et al. (2009) TNF-like weak inducer of apoptosis (TWEAK) induces inflammatory and proliferative effects in human kidney cells. Cytokine. 46: 24-35 |
| Antal Z, Jarchum I, DiLorenzo TP. (2008) HLA class I supertypes in type 1 diabetic children in an urban children's hospital. Annals of the New York Academy of Sciences. 1150: 86-9 |
| Jarchum I, Takaki T, DiLorenzo TP. (2008) Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities. Journal of Immunological Methods. 339: 66-73 |
| Mukhopadhaya A, Hanafusa T, Jarchum I, et al. (2008) Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 6374-9 |
| Jarchum I, Nichol L, Trucco M, et al. (2008) Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clinical Immunology (Orlando, Fla.). 127: 359-65 |
| Jarchum I, Baker JC, Yamada T, et al. (2007) In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice. Diabetes. 56: 2551-60 |