Sabrina A. Volpi, Ph.D.

Affiliations: 
2011 Yeshiva University, New York, NY, United States 
Area:
Molecular Biology, Immunology
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"Sabrina Volpi"

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Barbara K. Birshtein grad student 2011 Yeshiva University
 (Examining the Function of Elements hs5, 6 and 7 of the Immunoglobulin Heavy Chain 3' Regulatory Region through a Mouse Knockout Model.)
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Publications

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Huang D, Abbott RK, Havenar-Daughton C, et al. (2020) B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models. Proceedings of the National Academy of Sciences of the United States of America
Dong J, Panchakshari RA, Zhang T, et al. (2015) Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching. Nature. 525: 134-9
Volpi SA, Verma-Gaur J, Hassan R, et al. (2012) Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus. Journal of Immunology (Baltimore, Md. : 1950). 188: 2556-66
Chatterjee S, Ju Z, Hassan R, et al. (2011) Dynamic changes in binding of immunoglobulin heavy chain 3' regulatory region to protein factors during class switching. The Journal of Biological Chemistry. 286: 29303-12
Giambra V, Volpi S, Emelyanov AV, et al. (2008) Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus. Molecular and Cellular Biology. 28: 6123-33
Ju Z, Volpi SA, Hassan R, et al. (2007) Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3' regulatory region. The Journal of Biological Chemistry. 282: 35169-78
Garrett FE, Emelyanov AV, Sepulveda MA, et al. (2005) Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites. Molecular and Cellular Biology. 25: 1511-25
Coli R, Anderson SL, Volpi SA, et al. (2002) Genomic organization and chromosomal localization of the mouse IKBKAP gene. Gene. 279: 81-9
Anderson SL, Coli R, Daly IW, et al. (2001) Familial dysautonomia is caused by mutations of the IKAP gene. American Journal of Human Genetics. 68: 753-8
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