Brian R. Schram, Ph.D.

Affiliations: 
2003 Boston University, Boston, MA, United States 
Area:
Immunology, Cell Biology
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"Brian Schram"

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Thomas L. Rothstein grad student 2003 Boston University
 (NF-kappaB is required for surface immunoglobin-induced Fas-resistance in B cells.)
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Publications

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Schram BR, Tze LE, Ramsey LB, et al. (2008) B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements. Journal of Immunology (Baltimore, Md. : 1950). 180: 4728-41
Hippen KL, Schram BR, Tze LE, et al. (2005) In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance. Journal of Immunology (Baltimore, Md. : 1950). 175: 909-16
Tze LE, Schram BR, Lam KP, et al. (2005) Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. Plos Biology. 3: e82
Piatelli MJ, Wardle C, Blois J, et al. (2004) Phosphatidylinositol 3-kinase-dependent mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 and NF-kappa B signaling pathways are required for B cell antigen receptor-mediated cyclin D2 induction in mature B cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 2753-62
Schram BR, Rothstein TL. (2003) NF-kappa B is required for surface Ig-induced Fas resistance in B cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 3118-24
Owyang AM, Tumang JR, Schram BR, et al. (2001) c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 4948-56
Rothstein TL, Zhong X, Schram BR, et al. (2000) Receptor-specific regulation of B-cell susceptibility to Fas-mediated apoptosis and a novel Fas apoptosis inhibitory molecule. Immunological Reviews. 176: 116-33
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