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Kathleen A. McPhillips, Ph.D.

Affiliations: 
2006 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Pathology
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"Kathleen McPhillips"
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Peter M. Henson grad student 2006 University of Colorado, Denver
 (The role of oxidants in the clearance of apoptotic cells.)

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Fernandez-Boyanapalli R, McPhillips KA, Frasch SC, et al. (2010) Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 185: 4030-41
Borges VM, Vandivier RW, McPhillips KA, et al. (2009) TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L586-95
McPhillips KA, Erwig LP. (2009) Assessment of apoptotic cell phagocytosis by macrophages. Methods in Molecular Biology (Clifton, N.J.). 559: 247-56
Fernandez-Boyanapalli RF, Frasch SC, McPhillips K, et al. (2009) Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4. Blood. 113: 2047-55
Janssen WJ, McPhillips KA, Dickinson MG, et al. (2008) Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha. American Journal of Respiratory and Critical Care Medicine. 178: 158-67
Bianchi SM, Prince LR, McPhillips K, et al. (2008) Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa American Journal of Respiratory and Critical Care Medicine. 177: 35-43
BRATTON D, MCPHILLIPS K, BYRNE A, et al. (2008) IFNγ Enhances Efferocytosis by Macrophages (MΦ) in Chronic Granulomatous Disease (CGD) by a Nitric Oxide (NO) Dependent Mechanism Journal of Allergy and Clinical Immunology. 121: S84-S84
McPhillips K, Janssen WJ, Ghosh M, et al. (2007) TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 178: 8117-26
Morimoto K, Janssen WJ, Fessler MB, et al. (2006) Statins enhance clearance of apoptotic cells through modulation of Rho-GTPases. Proceedings of the American Thoracic Society. 3: 516-7
Morimoto K, Janssen WJ, Fessler MB, et al. (2006) Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 176: 7657-65
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