Bradley W. Doble, Ph.D.

Affiliations: 
2001 University of Manitoba, Winnipeg, Manitoba, Canada 
Area:
Cell Biology, Molecular Biology
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"Bradley Doble"

Parents

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Elissavet Kardami grad student 2001 University of Manitoba
 (Cardiac gap junctions: A target of growth factor signaling.)
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Publications

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Manoranjan B, Venugopal C, Bakhshinyan D, et al. (2020) Wnt activation as a therapeutic strategy in medulloblastoma. Nature Communications. 11: 4323
Zhang M, Lai Y, Krupalnik V, et al. (2020) β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus. Science Advances. 6: eaba1593
Moreira S, Polena E, Gordon V, et al. (2017) A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs. Cell Reports. 20: 2424-2438
Manoranjan B, Venugopal C, Pavlovic Z, et al. (2017) Abstract 5831: Activated Wnt signaling for the treatment of recurrent medulloblastoma Cancer Research. 77: 5831-5831
Khan KA, Dô F, Marineau A, et al. (2015) Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Molecular and Cellular Biology. 35: 3029-43
Meredith GD, D'Ippolito A, Dudas M, et al. (2015) Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells. Molecular Biology of the Cell. 26: 2139-50
Manoranjan B, Venugopal C, Mahendram S, et al. (2015) MB-15 * ACTIVATED Wnt SIGNALING TARGETS Sox2+ TREATMENT-REFRACTORY Shh-DEPENDENT MEDULLOBLASTOMA STEM CELLS Neuro-Oncology. 17: iii23-iii23
Bartman CM, Egelston J, Kattula S, et al. (2014) Gene Expression Profiling in Mouse Embryonic Stem Cells Reveals Glycogen Synthase Kinase-3-Dependent Targets of Phosphatidylinositol 3-Kinase and Wnt/β-Catenin Signaling Pathways. Frontiers in Endocrinology. 5: 133
Holowacz T, Alexson TO, Coles BL, et al. (2013) The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin. Biology Open. 2: 812-21
Mahendram S, Kelly KF, Paez-Parent S, et al. (2013) Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation. Plos One. 8: e65320
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