Robert D. Guzy, Ph.D.

Affiliations: 
2005 University of Chicago, Chicago, IL 
Area:
Cell Biology
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"Robert Guzy"

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Paul T. Schumacker grad student 2005 Chicago
 (Role of the mitochondrial electron transport chain in oxygen sensing and hypoxic HIF-1 alpha stabilization.)
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Publications

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El-Baz LMF, Shoukry NM, Hafez HS, et al. (2020) Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model. Iranian Journal of Allergy, Asthma, and Immunology. 19: 348-361
Lee TH, Yeh CF, Lee YT, et al. (2020) Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nature Communications. 11: 4254
Dorry SJ, Ansbro BO, Ornitz DM, et al. (2019) FGFR2 is Required for AEC2 Homeostasis and Survival Following Bleomycin-Induced Lung Injury. American Journal of Respiratory Cell and Molecular Biology
Reyfman PA, Walter JM, Joshi N, et al. (2018) Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine
Koo HY, El-Baz LMF, House SL, et al. (2018) Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation. The Journal of Pathology
Hamanaka RB, Nigdelioglu R, Meliton AY, et al. (2017) Inhibition of PHGDH Attenuates Bleomycin-induced Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology
Guzy RD, Li L, Smith C, et al. (2017) Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling. The Journal of Biological Chemistry
Guzy RD, Stoilov I, Elton TJ, et al. (2015) Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin. American Journal of Respiratory Cell and Molecular Biology. 52: 116-28
Waypa GB, Marks JD, Guzy RD, et al. (2013) Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation. American Journal of Respiratory and Critical Care Medicine. 187: 424-32
Loor G, Kondapalli J, Iwase H, et al. (2011) Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochimica Et Biophysica Acta. 1813: 1382-94
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