Paul T. Mungai, Ph.D.

2012 Cellular and Molecular Physiology University of Chicago, Chicago, IL 
Cell Biology, Physiology Biology, Molecular Biology
"Paul Mungai"


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Paul T. Schumacker grad student 2012 Chicago
 (Role of ROS in AMPK and CRAC channel activation during hypoxia or ischemia.)
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Tarigopula M, Davis RT, Mungai PT, et al. (2015) Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34
Ball MK, Waypa GB, Mungai PT, et al. (2014) Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α. American Journal of Respiratory and Critical Care Medicine. 189: 314-24
Waypa GB, Marks JD, Guzy RD, et al. (2013) Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation. American Journal of Respiratory and Critical Care Medicine. 187: 424-32
Mungai PT, Waypa GB, Jairaman A, et al. (2011) Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Molecular and Cellular Biology. 31: 3531-45
Jung HJ, Shim JS, Lee J, et al. (2010) Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. The Journal of Biological Chemistry. 285: 11584-95
Waypa GB, Marks JD, Guzy R, et al. (2010) Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells. Circulation Research. 106: 526-35
Chi AY, Waypa GB, Mungai PT, et al. (2010) Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells. Antioxidants & Redox Signaling. 12: 603-10
Iwase H, Robin E, Guzy RD, et al. (2007) Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Free Radical Biology & Medicine. 43: 590-9
Waypa GB, Guzy R, Mungai PT, et al. (2006) Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circulation Research. 99: 970-8
Ali MH, Mungai PT, Schumacker PT. (2006) Stretch-induced phosphorylation of focal adhesion kinase in endothelial cells: role of mitochondrial oxidants. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L38-45
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