Paul T. Mungai, Ph.D.

Affiliations: 
2012 Cellular and Molecular Physiology University of Chicago, Chicago, IL 
Area:
Cell Biology, Physiology Biology, Molecular Biology
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"Paul Mungai"

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Paul T. Schumacker grad student 2012 Chicago
 (Role of ROS in AMPK and CRAC channel activation during hypoxia or ischemia.)
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Publications

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Waypa GB, Smith KA, Mungai PT, et al. (2024) Mitochondria regulate proliferation in adult cardiac myocytes. The Journal of Clinical Investigation
Ball MK, Waypa GB, Mungai PT, et al. (2014) Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α. American Journal of Respiratory and Critical Care Medicine. 189: 314-24
Waypa GB, Marks JD, Guzy RD, et al. (2013) Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation. American Journal of Respiratory and Critical Care Medicine. 187: 424-32
Mungai PT, Waypa GB, Jairaman A, et al. (2011) Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Molecular and Cellular Biology. 31: 3531-45
Jung HJ, Shim JS, Lee J, et al. (2010) Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. The Journal of Biological Chemistry. 285: 11584-95
Waypa GB, Marks JD, Guzy R, et al. (2010) Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells. Circulation Research. 106: 526-35
Chi AY, Waypa GB, Mungai PT, et al. (2010) Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells. Antioxidants & Redox Signaling. 12: 603-10
Iwase H, Robin E, Guzy RD, et al. (2007) Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Free Radical Biology & Medicine. 43: 590-9
Loor G, Kondalpalli J, Dokic D, et al. (2007) Cardiomyocyte death in ischemia-reperfusion is mediated by opening of the mitochondrial permeability transition pore: Role of oxidant stress during ischemia Journal of the American College of Surgeons. 205: S21-S22
Waypa GB, Guzy R, Mungai PT, et al. (2006) Increases in mitochondrial reactive oxygen species trigger hypoxia-induced calcium responses in pulmonary artery smooth muscle cells. Circulation Research. 99: 970-8
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