Jana Barlic, Ph.D.

Affiliations: 
2001 The University of Western Ontario (Canada) 
Area:
Immunology, Cell Biology
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"Jana Barlic"

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David J. Kelvin grad student 2001 The University of Western Ontario (Canada)
 (beta-arrestin regulated CXCR1 internalization and signaling.)
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Publications

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Barlic J, Zhu W, Murphy PM. (2009) Atherogenic lipids induce high-density lipoprotein uptake and cholesterol efflux in human macrophages by up-regulating transmembrane chemokine CXCL16 without engaging CXCL16-dependent cell adhesion. Journal of Immunology (Baltimore, Md. : 1950). 182: 7928-36
Barlic J, Murphy PM. (2007) An oxidized lipid-peroxisome proliferator-activated receptor gamma-chemokine pathway in the regulation of macrophage-vascular smooth muscle cell adhesion. Trends in Cardiovascular Medicine. 17: 269-74
Barlic J, Zhang Y, Murphy PM. (2007) Atherogenic lipids induce adhesion of human coronary artery smooth muscle cells to macrophages by up-regulating chemokine CX3CL1 on smooth muscle cells in a TNFalpha-NFkappaB-dependent manner. The Journal of Biological Chemistry. 282: 19167-76
Barlic J, Murphy PM. (2007) Chemokine regulation of atherosclerosis. Journal of Leukocyte Biology. 82: 226-36
Barlic J, Zhang Y, Foley JF, et al. (2006) Oxidized lipid-driven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells through a peroxisome proliferator-activated receptor gamma-dependent pathway. Circulation. 114: 807-19
Sechler JM, Barlic J, Grivel JC, et al. (2004) IL-15 alters expression and function of the chemokine receptor CX3CR1 in human NK cells. Cellular Immunology. 230: 99-108
Barlic J, Sechler JM, Murphy PM. (2003) IL-15 and IL-2 oppositely regulate expression of the chemokine receptor CX3CR1. Blood. 102: 3494-503
Barlic J, Andrews JD, Kelvin AA, et al. (2000) Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI. Nature Immunology. 1: 227-33
Xu L, Khandaker MH, Barlic J, et al. (2000) Identification of a novel mechanism for endotoxin-mediated down-modulation of CC chemokine receptor expression. European Journal of Immunology. 30: 227-35
Barlic J, Khandaker MH, Mahon E, et al. (1999) beta-arrestins regulate interleukin-8-induced CXCR1 internalization. The Journal of Biological Chemistry. 274: 16287-94
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