Mythili Koneru, Ph.D.

Affiliations: 
2004 New York University, New York, NY, United States 
Area:
Cell Biology
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"Mythili Koneru"

Parents

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Alan B. Frey grad student 2004 NYU
 (Elucidating T cell dysfunction in the tumor microenvironment.)
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Publications

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Yeku OO, Purdon TJ, Koneru M, et al. (2017) Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment. Scientific Reports. 7: 10541
Rafiq S, Purdon TJ, Daniyan AF, et al. (2016) Optimized T-cell receptor-mimic (TCRm) chimeric antigen receptor T-cells directed towards the intracellular Wilms Tumor 1 antigen. Leukemia
Koneru M, Purdon TJ, Spriggs D, et al. (2015) IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo. Oncoimmunology. 4: e994446
Chang PS, Lee JC, Koneru M, et al. (2015) 408. CD19-Targeted CAR T Cells “Armored” To Secrete IL-12 Demonstrate Superior Efficacy Against B Cell Acute Lymphoblastic Leukemia and Resist Treg Immunosuppression Molecular Therapy. 23: S161
Lin SY, Yang J, Everett AD, et al. (2008) The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells. Experimental Cell Research. 314: 3107-17
Menon LG, Picinich S, Koneru R, et al. (2007) Differential gene expression associated with migration of mesenchymal stem cells to conditioned medium from tumor cells or bone marrow cells. Stem Cells (Dayton, Ohio). 25: 520-8
Koneru M, Monu N, Schaer D, et al. (2006) Defective adhesion in tumor infiltrating CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 6103-11
Koneru M, Schaer D, Monu N, et al. (2005) Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function. Journal of Immunology (Baltimore, Md. : 1950). 174: 1830-40
Simmons WJ, Koneru M, Mohindru M, et al. (2005) Tim-3+ T-bet+ tumor-specific Th1 cells colocalize with and inhibit development and growth of murine neoplasms. Journal of Immunology (Baltimore, Md. : 1950). 174: 1405-15
Radoja S, Saio M, Schaer D, et al. (2001) CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 5042-51
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