Jan Breslow

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Molecular Biology, Cell Biology
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"Jan Breslow"
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Publications

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Garbarino J, Pan M, Chin HF, et al. (2012) STARD4 knockdown in HepG2 cells disrupts cholesterol trafficking associated with the plasma membrane, ER, and ERC. Journal of Lipid Research. 53: 2716-25
Maxwell KN, Breslow JL. (2012) Antibodies to PCSK9: a superior way to lower LDL cholesterol? Circulation Research. 111: 274-7
Brown WV, Breslow J, Ballantyne C. (2012) Clinical use of genetic typing in human lipid disorders. Journal of Clinical Lipidology. 6: 199-207
Burkhardt R, Toh SA, Lagor WR, et al. (2010) Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. The Journal of Clinical Investigation. 120: 4410-4
Riegelhaupt JJ, Waase MP, Garbarino J, et al. (2010) Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism. Journal of Lipid Research. 51: 1134-43
Zhou C, King N, Chen KY, et al. (2009) Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice. Journal of Lipid Research. 50: 2004-13
Maxwell KN, Breslow JL. (2005) Proprotein convertase subtilisin kexin 9: the third locus implicated in autosomal dominant hypercholesterolemia. Current Opinion in Lipidology. 16: 167-72
Soccio RE, Adams RM, Maxwell KN, et al. (2005) Differential gene regulation of StarD4 and StarD5 cholesterol transfer proteins. Activation of StarD4 by sterol regulatory element-binding protein-2 and StarD5 by endoplasmic reticulum stress. The Journal of Biological Chemistry. 280: 19410-8
Maxwell KN, Fisher EA, Breslow JL. (2005) Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment. Proceedings of the National Academy of Sciences of the United States of America. 102: 2069-74
Soccio RE, Breslow JL. (2004) Intracellular cholesterol transport. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1150-60
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