Janus J. Bieker

Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Molecular Biology, Cell Biology
"Janus Bieker"
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Aimola IA, Inuwa HM, Nok AJ, et al. (2016) Cis-vaccenic acid induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. European Journal of Pharmacology. 776: 9-18
Liang R, Campreciós G, Kou Y, et al. (2015) A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis. Plos Genetics. 11: e1005526
Lohmann F, Dangeti M, Soni S, et al. (2015) The DEK oncoprotein is a critical component of the EKLF/KLF1 enhancer in erythroid cells. Molecular and Cellular Biology
Siatecka M, Soni S, Planutis A, et al. (2015) Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3). The Journal of Biological Chemistry. 290: 9929-40
Yien YY, Gnanapragasam MN, Gupta R, et al. (2015) Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues. Experimental Hematology. 43: 65-70
Soni S, Pchelintsev N, Adams PD, et al. (2014) Transcription factor EKLF (KLF1) recruitment of the histone chaperone HIRA is essential for β-globin gene expression. Proceedings of the National Academy of Sciences of the United States of America. 111: 13337-42
Manwani D, Bieker JJ. (2014) KLF1: when less is more. Blood. 124: 672-3
Xue L, Galdass M, Gnanapragasam MN, et al. (2014) Extrinsic and intrinsic control by EKLF (KLF1) within a specialized erythroid niche. Development (Cambridge, England). 141: 2245-54
Varricchio L, Dell'Aversana C, Nebbioso A, et al. (2014) Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells. The International Journal of Biochemistry & Cell Biology. 50: 112-22
Jaffray JA, Mitchell WB, Gnanapragasam MN, et al. (2013) Erythroid transcription factor EKLF/KLF1 mutation causing congenital dyserythropoietic anemia type IV in a patient of Taiwanese origin: review of all reported cases and development of a clinical diagnostic paradigm. Blood Cells, Molecules & Diseases. 51: 71-5
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