Shoukat Dedhar

University of British Columbia, Vancouver, Vancouver, BC, Canada 
Molecular Biology, Cell Biology
"Shoukat Dedhar"
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Tan J, Digicaylioglu M, Wang SXJ, et al. (2019) Insulin attenuates apoptosis in neuronal cells by an integrin-linked kinase-dependent mechanism. Heliyon. 5: e02294
Al-Ghabkari A, Deng JT, McDonald PC, et al. (2016) A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells. Scientific Reports. 6: 32118
Morris EJ, Assi K, Salh B, et al. (2015) Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Scientific Reports. 5: 8389
Chafe SC, Lou Y, Sceneay J, et al. (2015) Carbonic anhydrase IX promotes myeloid-derived suppressor cell mobilization and establishment of a metastatic niche by stimulating G-CSF production. Cancer Research. 75: 996-1008
Peng H, Talebzadeh-Farrooji M, Osborne MJ, et al. (2014) LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase. Cancer Research. 74: 1390-403
Teo ZL, McQueen-Miscamble L, Turner K, et al. (2014) Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Experimental Eye Research. 121: 130-42
Dai J, Matsui T, Abel ED, et al. (2014) Deep sequence analysis of gene expression identifies osteopontin as a downstream effector of integrin-linked kinase (ILK) in cardiac-specific ILK knockout mice. Circulation. Heart Failure. 7: 184-93
McDonald PC, Dedhar S. (2014) Carbonic anhydrase IX (CAIX) as a mediator of hypoxia-induced stress response in cancer cells. Sub-Cellular Biochemistry. 75: 255-69
Pan J, Lau J, Mesak F, et al. (2014) Synthesis and evaluation of 18F-labeled carbonic anhydrase IX inhibitors for imaging with positron emission tomography. Journal of Enzyme Inhibition and Medicinal Chemistry. 29: 249-55
McDonald PC, Sanghera J, Singh M, et al. (2014) Abstract 841: Therapeutic targeting of cancer cells in the hypoxic microenvironment using an orally bioavailable small molecule inhibitor of carbonic anhydrase IX Cancer Research. 74: 841-841
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