Kevin M. Shannon
Affiliations: | Biomedical Sciences | University of California, San Francisco, San Francisco, CA |
Area:
Cell Biology, Molecular BiologyGoogle:
"Kevin Shannon"Children
Sign in to add trainee| Suzanne Schubbert | grad student | 2007 | UCSF |
| Abigail L. Miller | grad student | 2011 | UCSF |
| Kegan L. Donlan | grad student | 2013 | UCSF |
| N. Monique Dail | post-doc | 2006-2014 | UCSF (Chemistry Tree) |
| Ari J. Firestone | post-doc | 2012-2015 | UCSF (Chemistry Tree) |
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Publications
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| Chen PY, Huang BJ, Harris M, et al. (2023) Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation. Jci Insight. 8 |
| Suciu RM, Luvaga IK, Hazeen A, et al. (2021) Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation. Bioorganic & Medicinal Chemistry Letters. 128414 |
| Remsberg JR, Suciu RM, Zambetti NA, et al. (2021) ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth. Nature Chemical Biology |
| Wong JC, Perez-Mancera PA, Huang TQ, et al. (2020) KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice. Jci Insight |
| Pucciarelli D, Angus SP, Huang B, et al. (2020) Nf1 mutant tumors undergo transcriptome and kinome re-modeling after inhibition of either mTOR or MEK. Molecular Cancer Therapeutics |
| Zambetti NA, Firestone AJ, Remsberg JR, et al. (2020) Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice. Blood |
| Wandler AM, Huang BJ, Craig JW, et al. (2020) Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia |
| Zambetti NA, Firestone AJ, Wong JC, et al. (2020) Abstract A25: In vivo evidence validating the palmitoylation/depalmitoylation cycle as a therapeutic target in NRAS mutant hematologic cancers Molecular Cancer Research. 18 |
| Meyer LK, Delgado-Martin C, Maude SL, et al. (2019) CRLF2 rearrangement in Ph-like acute lymphoblastic leukemia predicts relative glucocorticoid resistance that is overcome with MEK or Akt inhibition. Plos One. 14: e0220026 |
| Huang BJ, Wandler AM, Meyer LK, et al. (2019) Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias. Plos Genetics. 15: e1008168 |