Nicholas Denko

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Molecular Biology, Cell Biology
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"Nicholas Denko"
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Publications

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Wolfe AR, Cui T, Baie S, et al. (2024) Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions. Science Advances. 10: eadj3551
Benej M, Wu J, Kreamer M, et al. (2021) Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors. Cancers. 13
Benej M, Hong X, Vibhute S, et al. (2018) Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism. Proceedings of the National Academy of Sciences of the United States of America
O'Neill W, Golias T, Benej M, et al. (2017) Abstract 5467: Phosphoproteomic analysis of pyruvate dehydrogenase in response to environmental stress Cancer Research. 77: 5467-5467
Cerniglia GJ, Dey S, Gallagher-Colombo SM, et al. (2015) The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation. Molecular Cancer Therapeutics. 14: 1928-38
Denko NC. (2014) Hypoxic regulation of metabolism offers new opportunities for anticancer therapy. Expert Review of Anticancer Therapy. 14: 979-81
Sun RC, Denko NC. (2014) Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth. Cell Metabolism. 19: 285-92
Jaitin D, Sayles L, Goliazova T, et al. (2012) Abstract 1000: Oncogenic Kras inhibits mitochondrial metabolism by regulating the pyruvate dehydrogenase complex under conditions of nutrient stress Cancer Research. 72: 1000-1000
Spiotto MT, Banh A, Papandreou I, et al. (2010) Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. Cancer Research. 70: 78-88
Chen Y, Cairns R, Papandreou I, et al. (2009) Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect. Plos One. 4: e7033
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