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Klaus H. Kaestner

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology
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"Klaus Kaestner"
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Parents

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Heven Sze grad student 1986-1987 Penn

Children

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Kristen A. Lantz grad student 2004 Penn
Phuc V. Le grad student 2005 Penn
Rana K. Gupta grad student 2006 Penn
Irina M. Bochkis grad student 2008 Penn
Maria L. Golson grad student 2008 Penn
Sara D. Sackett grad student 2008 Penn
Geetu Tuteja grad student 2009 Penn
Lindsay B. McKenna grad student 2011 Penn
Sebastian Rieck grad student 2011 Penn

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Publications

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Su C, Gao L, May CL, et al. (2022) 3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk. Cell Metabolism. 34: 1394-1409.e4
Doliba NM, Rozo AV, Roman J, et al. (2022) α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals. The Journal of Clinical Investigation. 132
Lasconi C, Pahl MC, Pippin JA, et al. (2022) Variant-to-gene-mapping analyses reveal a role for pancreatic islet cells in conferring genetic susceptibility to sleep-related traits. Sleep
Fasolino M, Schwartz GW, Patil AR, et al. (2022) Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes. Nature Metabolism. 4: 284-299
Kondo A, Kaestner KH. (2021) FoxL1 mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development. Cells & Development. 165: 203662
Miao Z, Balzer MS, Ma Z, et al. (2021) Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets. Nature Communications. 12: 2277
Kondo A, Kaestner KH. (2021) FoxL1 mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development. Cells & Development. 165
Coate KC, Cha J, Shrestha S, et al. (2020) SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 are Expressed in the Pancreas but are Not Enriched in Islet Endocrine Cells. Biorxiv : the Preprint Server For Biology
Atkinson MA, Campbell-Thompson M, Kusmartseva I, et al. (2020) Organisation of the human pancreas in health and in diabetes. Diabetologia. 63: 1966-1973
Avrahami D, Wang YJ, Schug J, et al. (2020) Single cell transcriptomics of human islet ontogeny defines the molecular basis of β cell dedifferentiation in T2D. Molecular Metabolism. 101057
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