Tobey J. MacDonald

Affiliations: 
Molecular Medicine The George Washington University, Washington, DC, United States 
Area:
Oncology, Molecular Biology, Cell Biology
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"Tobey MacDonald"
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Publications

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Shahab SW, Roggeveen CM, Sun J, et al. (2023) The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival. Molecular Oncology
Kunhiraman H, McSwain L, Shahab SW, et al. (2023) IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma. Acta Neuropathologica Communications. 11: 62
Yuan L, Zhang H, Liu J, et al. (2021) STAT3 is required for Smo-dependent signaling and mediates Smo-targeted treatment resistance and tumorigenesis in Shh medulloblastoma. Molecular Oncology
MacDonald TJ, Liu J, Yu B, et al. (2021) Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo. Cancers. 13
Dobson THW, Tao RH, Swaminathan J, et al. (2019) Transcriptional repressor REST drives lineage stage-specific chromatin compaction at and increases AKT activation in a mouse model of medulloblastoma. Science Signaling. 12
Zhu D, Osuka S, Zhang Z, et al. (2018) BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. Cancer Cell. 33: 1004-1016.e5
Bhatia S, Baig NA, Timofeeva O, et al. (2015) Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization. Oncotarget. 6: 8929-46
McKinney N, Yuan L, Zhang H, et al. (2015) EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. Journal of Neuro-Oncology. 121: 109-18
Petersen W, Liu J, Yuan L, et al. (2014) Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283. Cancer Letters. 354: 68-76
Kieran MW, Yao X, Macy M, et al. (2014) FINAL RESULTS OF A PROSPECTIVE MULTI-INSTITUTIONAL PHASE II STUDY OF EVEROLIMUS (RAD001), AN MTOR INHIBITOR, IN PEDIATRIC PATIENTS WITH RECURRENT OR PROGRESSIVE LOW-GRADE GLIOMA. A POETIC CONSORTIUM TRIAL Neuro-Oncology. 16: iii27-iii27
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