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Isa Hussaini

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Cell Biology, Pathology, Oncology
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"Isa Hussaini"
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Parents

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Children

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Zachary A. Kohutek grad student 2009 UVA
Charles G. diPierro grad student 2011 UVA
Barbara C. Merk grad student 2011 UVA

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Publications

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Merk BC, Owens JL, Lopes MB, et al. (2011) STAT6 expression in glioblastoma promotes invasive growth. Bmc Cancer. 11: 184
Amos S, Redpath GT, Dipierro CG, et al. (2010) Epidermal growth factor receptor-mediated regulation of urokinase plasminogen activator expression and glioblastoma invasion via C-SRC/MAPK/AP-1 signaling pathways. Journal of Neuropathology and Experimental Neurology. 69: 582-92
Zhao Y, Xiao A, diPierro CG, et al. (2010) An extensive invasive intracranial human glioblastoma xenograft model: role of high level matrix metalloproteinase 9. The American Journal of Pathology. 176: 3032-49
Golding SE, Rosenberg E, Valerie N, et al. (2009) Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Molecular Cancer Therapeutics. 8: 2894-902
Kohutek ZA, diPierro CG, Redpath GT, et al. (2009) ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4605-15
Zhao Y, Xiao A, Dipierro CG, et al. (2008) H-Ras increases urokinase expression and cell invasion in genetically modified human astrocytes through Ras/Raf/MEK signaling pathway. Glia. 56: 917-24
Li Y, Guessous F, Kwon S, et al. (2008) PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations. Cancer Research. 68: 1723-31
Amos S, Mut M, diPierro CG, et al. (2007) Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion. Cancer Research. 67: 10241-51
Hussaini IM, Trotter C, Zhao Y, et al. (2007) Matrix metalloproteinase-9 is differentially expressed in nonfunctioning invasive and noninvasive pituitary adenomas and increases invasion in human pituitary adenoma cell line. The American Journal of Pathology. 170: 356-65
Uht RM, Amos S, Martin PM, et al. (2007) The protein kinase C-eta isoform induces proliferation in glioblastoma cell lines through an ERK/Elk-1 pathway. Oncogene. 26: 2885-93
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